Overzealous reactions to takedown notifications can and do severely damage real people and organizations. The "guilty until proven innocent" provisions mean that complaints that used to be handled via a single email between interested parties very quickly devolve into a real denial of service for people that aren't even necessarily related to the "infringer." In this case, an upstream provider actually deleted a customer's SQL database, which had to be restored from backup. How crazy is that?
Life is a concentration camp. You’re stuck here and there’s no way
out and you can only rage impotently against your persecutors.
— Woody Allen