Overzealous reactions to takedown notifications can and do severely damage real people and organizations. The "guilty until proven innocent" provisions mean that complaints that used to be handled via a single email between interested parties very quickly devolve into a real denial of service for people that aren't even necessarily related to the "infringer." In this case, an upstream provider actually deleted a customer's SQL database, which had to be restored from backup. How crazy is that?
Claret is the liquor for boys; port for men; but he who aspires to be a hero
… must drink brandy.
— Samuel Johnson